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275 Epidemiology of Poliomyelitis and Management of Acute Ascending Flaccid Paralysis (AAFP) in Paediatric Intensive Care Unit (PICU) in Algeria
  1. MA Negadi,
  2. H Bouguetof,
  3. K El Halimi,
  4. D Boumendil,
  5. ZC Mentouri
  1. Pediatric Intensive Care Unit, Faculty of Medicine, Oran University, Oran, Algeria

Abstract

Background and Aims As part of the implementation of National plan for the eradication of poliomyelitis, disease surveillance and management of cases of AAFP are key strategies of this program.

The aim is participation in the national program for poliomyelitis, eradication and to determine the efficacy of intravenous immunoglobulin (IG) for treatment of AAFP.

Methods From September 1994 to February 2012, 176 cases of AAFP were identified and supported in our PICU. Since January 2008, 25 children were treated by IG. The parameter studied were: age, gender, autonomic disorders, albuminocytologic dissociation of CSF after lumbar puncture, artificial ventilation, average time of stay, and mortality.

Results In this series, no case of poliomyelitis has been diagnosed by the Pasteur Institute of Algeria. Since 2008, use of IG seems to improve the mortality. 8%in the overall series (n = 176) vs 4% in the group treated with immunoglobulins (n = 25). All deaths are related to the existence of severe neurovegetative disorders. The need in ventilation and the duration of stay does not appear to be influenced by the use of the “IG”.

Conclusion The eradication of poliomyelitis is a national goal to declare the Algeria zone free of polio by the WHO.

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