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1433 Vitamin D Deficiency and Secondary Hyperparathyroidism in Obese Children
  1. R Ghergherehchi1,
  2. N Hazhir2,
  3. A Tabrizi2
  1. 1Pediatric Endocrinology, Tabriz University of Medical Sciences
  2. 2Tabriz Children Hospital University of Medical Sciences, Tabriz, Iran

Abstract

Obesity subjects individuals into metabolic and endocrine disorders. Thus obesity may increase the risk of vitamin D deficiency. This text aims at studying the prevalence of vitamin D deficiency and secondary hyperparathyroidism in obese children. In a non-randomized case control study on 52 obese children (body mass index (BMI)>95th percentile) aged 4 to 16 years undertaken at the outpatient endocrine clinic of the Children Hospital at Tabriz University between 2009–2011. This study was conducted to compare the prevalence of vitamin D deficiency and secondary hyperparathyroidism in obese children compared with 57 non obese (BMI< 85th percentile). 109 children including 52 (50.5%) boys and 57 (49.5%) girls were studied. Most of case (76.9%) and control (42.1%) groups suffered from degrees of vitamin D deficiency. There was meaningful statistical difference between two groups considering to vitamin D deficiency and parathyroid hormone (p = 0.001). A negative relations was found between iPTH and vit D level (p<0.001, r=–0.2), BMI and 25-OH vit D (p<0.001, r=–0.2). A positive relation was observed between parathyroid hormone and BMI (p=0.009, r=0.1). Obese children are at high risk at vitamin D deficiency and secondary hyperparathyroidism. BMI appears to be an important risk factor for vitamin D deficiency.

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