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1150 The Incidence and Risk Factors of the Congenital Cardiac Malformations in Newborn
  1. B Popovici,
  2. M Mitrica
  1. Pediatric, Faculty of Medicine, ‘Transilvania’ University Brasov, Brasov, Romania


Introduction Congenital malformations are still a major cause of morbidity and mortality in newborns in Romania. The significant incidence and the difficulties of the management of this pathology are a reality which requires more attention and efforts.

Objective The aim of the study was to determine the incidence of congenital cardiac malformations (CCM) between 2000–2010, the risk factors and distribution of the CCM.

Material and method It was a retrospective study which included all the newborns with CCM who were admitted in our hospital. We had proceeded: clinical exam, laboratory tests, ECG, echocardiography.

Results From a total of 105968 children, 863 had congenital cardiac malformations (0.81%). The main risk factors were: teratogenic factors (diabetes mellitus and alcoholism), cromosomal defects, multifactorial transmision. The most frequent malformations were noncyanotic as atrial septal defects and ventricular septal defects (88.06%) vs cyanotic defects (11.93%). In most of the cases the diagnosis was estabilished after birth and only 1.73% (nr=15 cases) had prenatal diagnosis. The outcome of children was: 504 newborns (58.40%) had needed medical treatment but no surgical corrective procedures, 223 (25.84%) had had paleative or corrective surgical treatment and 136 (15.75%) had died because of complications or of the imposibility of a proper surgical treatment.

Conclusions The diagnosis of cardiac malformation is not a problem anymore due to echocardiography but, unfortunatly, prenatal diagnosis is still difficult. The most cases are noncyanothic malformations. The outcome is related with the type of CCM, complications and possibility of a proper treatment.

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