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1075 Risk Factors for Posthemorrhagic Hydrocephalus in a Neonatal Intensive Care Unit
  1. F Kulalı1,
  2. N Altuntas1,
  3. E Kazancı1,
  4. S Aktas1,
  5. S Unal1,
  6. I Hirfanoglu1,
  7. E Onal1,
  8. C Turkyılmaz1,
  9. E Koc1,
  10. Y Atalay1,
  11. E Ergenekon1,
  12. K Gucuyener2
  1. 1Pediatrics/Newborn Medicine
  2. 2Pediatrics, Pediatric Neurology, Gazi University Hospital, Ankara, Turkey


Background and aim Post-hemorrhagic hydrocephalus (PHH) is one of the most serious complications of intraventricular hemorrhage (IVH) in a newborn. Causes are multifactorial including genetical, pre and postnatal complications. Conditions assosciated with hydrocephalus following IVH were investigated.

Methods Charts of patients admitted to the neonatal intensive care unit (NICU) over last 5 years were investigated retrospectively, newborns with grade 3–4 IVH were analyzed for risk factors in the perinatal and neonatal period. Ones with and without hydrocephalus were compared. Results are expressed as median and range and percentage where required.

Results 24 newborns were diagnosed with IVH, 9 of whom developed hydrocephalus. Most significant risk factors are shown in table 1.

Abstract 1075 Table 1

Hypotension, asidosis, were more frequent in the PHH group. GA, BW, Apgar scores, lowest-highest CO2, Crib score are shown in table 2.

Abstract 1075 Table 2

Highest CO2 in the first 10 days of life was significantly higher in the PHH group (p=0.044).

Conclusion PHH remains to be one of the most severe complications of IVH. In this small group of patients, high CO2 levels, hypotension seem to be important risk factors.

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