Background C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and leukocyte count are used in several studies, for evaluation of invasive bacterial infections.
Aim Aim of the study to evaluate the usefulness of leukocytes, CRP and ESR as identifiers of invasive bacterial infections at children.
Methods We have prospectively evaluated 705 patients divided into two groups: 1) group A with 110 patients having invasive bacterial infections and 2) group B with localized bacterial infections comprised of 595 patients.
Results Mean values for leucocytes was 12536±6642/mm3 for invasive bacterial infections versus 11263±5285/mm3 for localized bacterial infections (p<0.05).
Mean ESR for invasive infections was 31, 13± 29, 11 mm/hr versus 25, 94±22, 93 mm/hr for localized infections (p<0.08). Mean CRP for invasive infections was 42, 57±25, 45 mg/dl versus 24.10±13.58 mg/dl (p<0.04) for localized bacterial one.
Conclusion This study suggests that CRP, ESR and leucocytes are good indicators in diagnose of invasive bacterial infections.