Background and Aims In recent years the problem of mycoplasmal pneumonia, especially in early age children attracted the attention of pediatricians around the world. Purpose - to study the peculiarities of clinical course of mycoplasmal pneumonia in early age children.
Methods From 2009 to 2011 among children with pneumonia analyzed for the presence of mycoplasmal pneumoniae. The study involve 450 children aged 5 months to 3 years. Antibodies to Mycoplasma pneumoniae were detected by ELISA in 60 children. Raising antibodies indicated more than 4 times. Conducted clinical observations, X-ray methods, the method of ELISA for the detection of IgM antibodies to Mycoplasma pneumoniae, DNA display M. pneumoniae in sputum by PCR.
Results Mycoplasmal pneumonia began sharply at 80% of children with high fever, cough was dry and unproductive. Outpatient treatment starting antibiotics penicillin group did not give the effect. Pyrexia over 38°C was observed in 95% of children.
On radiographic studies, the bilateral homogeneous lobular infiltration revealed in the lungs at the majority of children (75%). Segmental nature of the infiltrative changes detected in 5% right-sided focal character pneumonic process occurred in 20%, left-side lung had 9.5% of children. In the analysis of peripheral blood revealed anemia in 25% of children, moderate leukocytosis in 89%, marked lymphocytosis (95%) and accelerated erythrocyte sedimentation rate (89%).
Conclusion For early age children with mycoplasmal pneumonia is characterized by severe intoxication, prolonged dry cough. On the radiograph indicated bilateral focal mainly infiltration. In the hemogram - a moderate leukocytosis, lymphocytosis, ESR acceleration.