Background Pediatric lymphadenopathy is a challenging medical situation for the patient, the parent, and the physician. Although the bulk of these masses will be benign the fear of malignancy is omnipresent. Therefore, the objective of this study was to identify the common causes of lymphadenopathy among Sudanese children.
Methods One hundred pediatric patients presenting with peripheral lymphadenopathy were included in the study, their ages ranging from 2 to 14 years, with a mean age of 7 years. Demographic characteristics, clinical manifestations and FNA materials were prospectively obtained.
Results FNA was performed under general anesthesia in 100 cases (100%). There were no technical complications. All cases confirmed adequacy of specimen. Overall, FNA demonstrated 90(90%) benign lesions and 10(10%) malignant diagnosis. The benign lesion was reactive lymphoid hyperplasia (n = 64), followed by benign granulomatous disease (n = 26). Of the 10 cases diagnosed with malignancy, 7 (70%) were cases of non-Hodgkin′s lymphoma and the remaining 3 (3%) were Hodgkin′s lymphoma cases.
Conclusion lymphoblastic leukemia can be suspected in pediatric patients with lymphadenopathy. FNA provides a useful tool in the diagnosis of pediatric patients with peripheral lymphadenopathy.