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692 Increasing the Frequency of Eosinophilic Esophagitis in Children: Is it Real?
  1. O Beser1,
  2. E Celik2,
  3. S Lacinel2,
  4. T Erkan1,
  5. T Kutlu1,
  6. FC Cokugras1
  1. 1Pediatric Gastroenterology, Hepatology and Nutrition
  2. 2Dept. of Pediatrics, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey

Abstract

Introduction Eosinophilic esophagitis(EOE) is a chronic esophageal inflammatory disease. Because signs and symptoms of the disease are similar to the gastroesophagial reflux (GER) disease many patients are treated as GERdisease.

Aim In this study we aim to evaluate 42 children with the diagnosis of EOE.

Methods Clinical and laboratuary databases of 42 patients who were followed-up.

Results 57% of patients was male, mean age 7.24±3.8.IgE levels were high in 24 patients of the all patients. Skin prick test was applied to the patients who have high IgE levels however the factor that may cause allergies could be detected in 1/2 of them. We applied gastroscopy to all patients and nodular appearance was seen in 90% of them. Biopsy specimens of all cases had at least 15 eosinophils infiltration. Food elimination was performed to 12 patients whose allergic factor was detected by skin pirck test. Antihistaminic treatement was applied to 12 cases and four of them had systemic steroid treatment. 8 cases were treated by montelukast and topical steroid treatment. Complaints of thirty eight patients who did not have systemic steroid treatment were relieved in the end of first month however four patients that had to use steroids relieved in the end of the second month.

Conclusion EOE is increasing everyday. Complaints and the findings are similar to much of GER disease however it should be considered first in patients whose complaints are going on desipite the GERD treatment. Treatment costs and the quality of life is high in terms of early response to treatment in pediatric patients which is recognizable form of the disease is gaining importance.

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