Backgrounds and aims Pilomatrixoma commonly occurs in children as a single tumor. Multiple tumors are rare. This case report describes the presentation of an 8-year-old girl with multiple pilomatrixomas.
Case Report An 8-year-old girl presented with 4 subcutaneous, rock-hard nodules. The average time from the onset of the appearance of other nodules was about 12 months. The sites of occurrence were the right eyebrow, neck, right scapular region, and upper left region of the abdomen. Only the nodule in the abdominal region was 1 cm in diameter, the others were 5 mm in diameter. The nodules were nontender and painless except the 1 in the right scapular region. The overlying skin was normal in appearance, with no evidence of ulceration or discoloration. No concurrent disorders were observed. The preliminary clinical diagnosis was multiple pilomatrixoma. The nodules were tender and painful, and the larger one was surgically excised. Histologically, the nodules consisted of acellular material in which ghost cells (figure-1) were prominent, together with foreign body giant cells and calcification. At the periphery, there were focal areas of basaloid cells (figure-2). The pathological diagnosis was pilomatrixoma. No recurrence has been observed during 8 months’ follow-up.