Background and Aims The aims of this study was to determine if the time of introduction and diary quantity of amino acid offered at first 35 days of life for newborns with BPD, weight < 1500g at birth, may influence the oxygen dependence at final period.
Methods Newborns with BPD, consecutively observed in the NICU (UFF - RJ - Brazil), from April 2006 to March 2008, were divided in Early Start (ES) and Late Start (LE) Groups when they began to received amino acids (AA) up (n=56) or after (n=48) 72 hours of life. It was also divided according to the quantity of AA administered in the first week of life (1.11± 0.04g/kg/day): Larger Supply (LAS) (n=42) and Lower Supply (LOS) (n=58) received a quantity of AA 2 SD above or below this mean.
Results A total of 104 newborns were evaluated. At 35th of life the babies of ES and LE were weighing 34.1% and 21.9% more than his weight at birth, respectively, and from LOS and LAS, 39% and 23.7% regarding his birth (p>0.05). At the end of the studied period, 8.9% of the babies of the ES and 16.7% of the LE still stayed receiving some oxygen. In LAS 4.7% and 21% in LOS were receiving some oxygen support (p = 0.004).
Conclusion Nutritional state is decisive in the oxygen necessity at neonatal final period, and the major offers of protein is a priority way.
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