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527 Chemoterapeutic Treatment of Rhabdomyosarcoma Botryoide
  1. F Selimi1,
  2. V Grajqevci-Uka1,
  3. R Macastena-Maxhuni1,
  4. B Abrashi1,
  5. V Hasbahta2
  1. 1Hemato-Oncology Department
  2. 2Gastroenterology Department, Pediatric Clinic, University Clinical Centre of Kosovo, Prishtina, Kosovo

Abstract

Introductions Rhabdomyosarcoma (RMS) is malignant tumor which arises from embryonic muscle cells. RMS is the most common type of soft-tissue cancer in children. It can develop on children at any age, but it's most common in those between 2 and 6 years old and 15 and 19 years old.

Purpose Presentation of the case with RMS botryoides, which was presented to the Hematology/Oncology Unit at Pediatric Clinic and has received chemotherapy treatment.

Materials and Methods A female child, 2 years old, who was initially admitted in Clinic University Centre of Tirana, with presence the mass of tumor in vulvovaginal region. The tumor mass appeared after the birth and it has been increasing in size since then. At University Clinic Center of Tirana the patient has been operated, and the tumor has been removed from her. Detailed Histopathological analyses has shown that the removal part of her was botryoide Rhabdomyosarcoma. The diagnose of the patient was made based on anamnesis, clinical examination, laboratory tests, radiological images, bone marrow aspiratione, histopathological analysis. After the diagnoses it was indicated the treatment protocol of chemotherapy for extracranial rhabdomyosarcoma VAC.

Conclusion The total Resection of the tumor mass, the application of the protocol for RMS botryoide, supportive care, monitoration of the chemotherapy toxicity has resulted in absence of minimal residual disease, which is confirmed by the follow up of her clinical status, laboratory tests, radiology tests, that has resulted the absence of secondary deposits.

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