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416 Impact of Exercise on Lower Activity Levels in Children with Acute Lymphoblastic Leukemia: A Randomized Controlled Trial From Turkey
  1. M Kurtuncu Tanir1,
  2. S Kuguoglu2
  1. 1Pediatric Nursing, Zonguldak Karaelmas University, Zonguldak, Turkey
  2. 2Pediatric Nursing, Emeritus Professor from Marmara University, Brooklyn, NY, USA


Background and Aims Children with Acute lymphoblastic leukemia (ALL) exhibit body function disorders and activity limitations at an early stage. A study assessing the impact of activities and health-related quality of life of initiatives physical exercise in children with ALL were not found in Turkey. This study was carried out to determine the effects of an exercise program on both physical parameters and on quality of life in children with ALL.

Methods A total of 41 children with ALL at two university hospitals were accepted into the study. Due to the demise of one of the children in the trial group, the study was completed with 19 trial and 21 control patients, a total of 40 children and their parents. The two groups were formed by randomized selection. The study was implemented in the children’s homes and in the clinical environment and in the period 2007–2008.

Results When the trial subjects were assessed in terms of their mean scores in the 9-Minute Walk Test, the Timed Up and Down Stairs Test, the Timed Up and Go Test, the measurements of their leg muscle strength, their hemoglobin and hematocrit tests, a decidedly significant increase was seen compared to the control group (p<0.05).

Conclusions Regular and systematic exercise regimens implemented by children with ALL have resulted in improved testing results, enhanced physical performance, and better laboratory results compared to a control group and to children’s scores prior to the initiation of such a program.

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