Investigation and management of hypercalcaemia in children
- 1Department of Paediatric Endocrinology, University Hospital Southampton, Southampton, UK
- 2Department of Endocrinology and Diabetes, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, UK
- Correspondence to Dr Justin Huw Davies, Department of Paediatric Endocrinology, University Hospital Southampton, Tremona Road, Southampton SO16 6YD, UK;
Contributors Both authors contributed to the writing of this manuscript.
- Accepted 1 February 2012
- Published Online First 23 March 2012
Hypercalcaemia is a far less common finding in children than in adults. It may present with characteristic symptoms or may be identified as a coincidental finding in children investigated for a variety of complaints. Assessment of hypercalcaemia requires an understanding of the normal physiological regulation of plasma calcium by the combined actions of parathyroid hormone, 1,25-dihydroxyvitamin D3 and the calcium sensing receptor. Hypercalcaemia will usually require treatment using a number of different modalities but occasionally it can be due to a benign asymptomatic condition that requires no intervention. This article presents a logical approach to the investigation and subsequent management of this condition.
Competing interests None.
Provenance and peer review Commissioned; externally peer reviewed.