Higher rates of behavioural and emotional problems at preschool age in children born moderately preterm
- 1Department of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, The Netherlands
- 2Department of Paediatrics, Division of Neonatology, University Medical Center Groningen, University of Groningen, The Netherlands
- Correspondence to Marieke R Potijk, Department of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, PO Box 196, 9700 AD Groningen, The Netherlands;
- Received 1 April 2011
- Accepted 21 October 2011
- Published Online First 6 December 2011
Objective To compare preschool children born moderately preterm (MP; 32–35 weeks' gestation) and children born at term (38–41 weeks' gestation) regarding the occurrence of behavioural and emotional problems, overall, for separate types of problems and by gender.
Design Prospective cohort study consisting of a community-based sample of MP and a random sample of term-born children in 13 Preventive Child Healthcare centres throughout the Netherlands.
Patients 995 MP and 577 term-born children just under age 4 were included.
Main outcome measures Behavioural and emotional problems were measured using the Child Behavior Checklist 1.5–5 years. Seven syndrome scales, internalising, externalising and total problems were determined. Higher scores indicate worse outcomes.
Results MP children had higher scores on all syndrome scales, internalising, externalising and total problems than term-born controls. The mean difference on total problems was 4.04 (95% CI 2.08 to 6.00). Prevalence rates of elevated externalising problem scores were highest in boys (10.5%) and internalising problems were highest in girls (9.9%). MP children were at greater risk for somatic complaints (OR 1.92, 95% CI 1.09 to 3.38), internalising (OR 2.40, 95% CI 1.48 to 3.87), externalising (OR 1.69, 95% CI 1.07 to 2.67) and total problems (OR 1.84, 95% CI 1.12 to 3.00).
Conclusions Moderate preterm birth affects all domains of behavioural and emotional problems, particularly for girls. MP children should be targeted for the prevention of mental health problems as they have a great impact on developmental and social competencies at school and in the community.
Competing interest None.
Funding This study is part of a larger cohort study on the development, growth and health of children born preterm (controlled-trials.com ISRCTN 80622320) and is supported by the research foundation of Beatrix Children's Hospital, the Cornelia Foundation for the Handicapped Child, the A. Bulk-Child Health Care Research Fund, the Dutch Brain Foundation, and unrestricted research grants from Friesland Campina, Hero, Abbott and Pfizer Europe. Marieke Potijk was supported by a grant from the Junior Scientific Masterclass of the University of Groningen. The financers had no role at any stage of the project including the decision to submit the manuscript.
Provenance and peer review Not commissioned; externally peer reviewed.