Subclinical hypothyroidism in childhood
- Correspondence to Dr D Cody, Department of Endocrinology and Diabetes, Our Ladys Childrens Hospital, Crumlin, Dublin 12, Ireland;
- Accepted 23 January 2010
- Published Online First 22 April 2010
Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated. Currently there is no broad consensus on the investigation and treatment of these patients; specifically who to treat and what cut-off level of TSH should be used. This paper reviews the available evidence regarding investigation, treatments and outcomes reported for childhood SH.
Provenance and peer review Commissioned; externally peer reviewed.
Patient consent Not obtained.