Determinants of partial or no primary immunisations
- L J Jessop1,
- C C Kelleher1,
- C Murrin1,
- J Lotya1,
- A T Clarke1,2,
- D O'Mahony1,
- U B Fallon2,
- H Johnson3,
- G Bury4,
- A W Murphy5,
- The Lifeways Cohort Study Steering Group
- 1School of Public Health and Population Science, Woodview House, University College Dublin, Dublin, Ireland
- 2HSE Dublin Mid-Leinster Area Offices, Tullamore, Co. Offaly, Ireland
- 3Health Information Unit, Health Intelligence, HSE, Dr Steevens Hospital, Dublin, Ireland
- 4School of Medicine and Medical Science, University College Dublin, Coombe Healthcare Centre, Dublin, Ireland
- 5Department of General Practice, National University of Ireland, Galway, Ireland
- Correspondence to Professor Cecily Kelleher, School of Public Health and Population Science, Woodview House, University College Dublin, Belfield, Dublin 4, Ireland;
Contributors The Lifeways Cross Generation Cohort Study was established in 2000 by a research steering group that includes CCK, GB and AWM. LJJ devised the present analysis and wrote the first draft of the article, CCK is coauthor, supervisor of the study, a Principal Investigator (PI) for the Lifeways cohort study and is guarantor, CM devised the study instruments, DOM was the data manager and assisted with data linkage, ATC provided input in interpretation of findings, JL assisted with the statistical analysis, GB and AWM oversaw the linkage procedure, HJ and UBF provided the linked immunisation records. All authors assisted in drafting the paper and gave input into the interpretation of findings.
- Accepted 23 February 2010
- Published Online First 1 June 2010
Objective To determine if different factors affect children having full, partial or no primary immunisations.
Methods This was a crossgenerational cohort study with linkage to primary care and hospital records conducted in urban and rural settings in Ireland, recruiting in 2001–2003 with 5-year follow-up. A total of 749 children with immunisation information took part.
Results The uptake of reported primary immunisations was 92.8% full, 4.9% partial and 2.3% no primary immunisations. Adjusted relative risk ratios for children receiving no primary immunisations were significant for: having a mother who had ever visited an alternative practitioner 3.69 (1.05 to 12.9), a mother with means tested full general medical services eligibility 8.11 (1.58 to 41.65), a mother who scored <50 for the World Health Organization Quality of Life (WHO-QOL) scale psychological domain 8.82 (1.79 to 43.6) or living in the west of Ireland (rural) 3.64 (1.0 to 13.2). Being born prematurely was associated with partial primary immunisation, adjusted OR 4.63 (1.24 to 17.3).
Conclusions Knowledge of these differences will help target campaigns to increase full uptake of primary immunisations.
Funding The Health Research Board of Ireland has supported all sweeps associated with this study. The work is independent of the funding sources.
Competing interest None.
Ethics approval Ethics approval was granted by the UCD ethics committee for 2007 sweep, and for original recruitment and follow-up stage by the Irish College of General Practitioners ethics committee and respectively, ethics committees of Coombe University Hospital Dublin and University College Hospital Galway.
Provenance and peer review Not commissioned; externally peer reviewed.