Chlamydia trachomatis respiratory infection in Dutch infants
- G I J G Rours1,5,
- M R Hammerschlag2,
- G J J Van Doornum3,
- W C J Hop4,
- R de Groot1,
- H F M Willemse5,
- H A Verbrugh5,
- R P Verkooyen5
- 1Division of Paediatric Infectious Diseases & Immunology, Department of Paediatrics, Erasmus MC, Rotterdam, The Netherlands
- 2Division of Pediatric Infectious Diseases, Department of Pediatrics, State University of New York Downstate Medical Center, Brooklyn, New York, USA
- 3Department of Virology, Erasmus MC, Rotterdam, The Netherlands
- 4Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, The Netherlands
- 5Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands
- Correspondence to Dr G I J G Rours, Department of Paediatrics, Erasmus MC, Dr Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands; g.rours{at}erasmusmc.nl
- Accepted 23 March 2009
- Published Online First 23 April 2009
Abstract
Chlamydia trachomatis is the most common bacterial pathogen causing sexually transmitted infections in Dutch adults. As prenatal screening for C trachomatis and treatment of pregnant women is not routine practice in The Netherlands, perinatal transmission of C trachomatis may therefore occur. The presence of C trachomatis in infants less than 6 months of age who presented with respiratory complaints to the Erasmus MC-Sophia hospital was evaluated. Respiratory specimens, primarily nasopharyngeal swabs, were tested for C trachomatis, respiratory viruses and Mycoplasma pneumoniae using PCR, viral isolation in cell cultures and direct immunofluorescence. C trachomatis respiratory tract infection was confirmed to be relatively common with detection in 10 of 148 (7%) infants tested. C trachomatis had not been tested for by the attending physicians, but was the second most frequently detected respiratory pathogen after human Respiratory Syncitial Virus, which was found in 41 (28%) infants.
Footnotes
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Competing interests None.
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Ethics approval Ethics approval was provided by Erasmus MC.








