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A retrospective study of neonates with congenital diaphragmatic hernia (CDH) was conducted at Great Ormond Street Hospital, a tertiary paediatric centre, between January 1995 and December 2006 with comparison of two treatment periods of 6 years each. Management and 1-year survival rates of 147 consecutive patients using the oxygenation index to assess the severity of acute respiratory failure were analysed. In the first 6 years (January 1995 to December 2000, period 1) 64 neonates were admitted and in the second 6 years (January 2001 to December 2006, period 2) 83 neonates were treated.
Early management …