Article Text

PDF
Isotonic maintenance fluids do not produce hypernatraemia
  1. M L Moritz1,
  2. C Ayus2
  1. 1
    Division of Nephrology, Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
  2. 2
    Renal Consultants of Houston, Houston, TX, USA
  1. Michael L Moritz, Division of Nephrology, Children’s Hospital of Pittsburgh, 3705 Fifth Ave, Pittsburgh, PA 15213-2538, USA; michael.moritz{at}chp.edu

Statistics from Altmetric.com

Coulthard proposes that 0.18% saline should be the maintenance fluid of choice in children and that an intravenous fluid with a sodium composition of 0.45% saline or higher will lead to more cases of hypernatraemia.1 His arguments are based primarily on two false premises: (i) that the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is extremely rare and (ii) that renal concentrating defects are common. In 2003, we proposed the use of 0.9% saline as a maintenance parenteral fluid for the prevention of hospital-acquired hyponatraemia, as hypotonic fluids were associated with numerous cases of death and neurological injury from hyponatraemic encephalopathy …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.