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Lipoprotein(a) (Lp(a)) is a distinctive cholesterol-rich lipoprotein complex in blood. Population studies show that Lp(a) levels are not normally distributed but are skewed towards low concentrations of <10 mg/dl−1.1 Only 20% of Caucasians are thought to have levels >30 mg/dl−1, the threshold level nominated for cardiovascular disease (CVD) risk in both children and adults.1 Although Lp(a) takes the form of an independent risk factor,1 it is the combined elevated levels of Lp(a) and low-density lipoprotein cholesterol (LDL-C), or Lp(a) and fibrinogen (Fg) that is thought to have the greatest detrimental effect.2 3
We determined the Lp(a) concentrations in schoolchildren aged 12–13 years in South Wales, as well as the percentage of children exhibiting …
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