rss
Arch Dis Child 2009;94:855-859 doi:10.1136/adc.2008.150870
  • Original article

Pubertal anthropometry in sons and daughters of women with preeclamptic or normotensive pregnancies

  1. B Ogland1,2,
  2. L J Vatten2,3,
  3. P R Romundstad2,
  4. S T Nilsen3,
  5. M R Forman4
  1. 1
    Department of Pediatrics, Stavanger University Hospital, Stavanger, Norway
  2. 2
    Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway
  3. 3
    Stavanger University Hospital, Stavanger, Norway
  4. 4
    MD Anderson Cancer Center, Houston, Texas, USA
  1. Correspondence to Dr Bjorn Ogland, Neonatal Intensive Care Unit, Rikshospitalet University Hospital, N-0027 Oslo, Norway; bogland{at}online.no
  • Accepted 17 June 2009
  • Published Online First 1 July 2009

Abstract

Objective: To compare body mass index (BMI) and waist and hip circumference in early puberty (10.8 years in girls and 11.8 years in boys) among offspring of preeclamptic and normotensive pregnancies.

Design: Population based follow-up study.

Methods: Anthropometry measured in early puberty in 91 girls and 92 boys of preeclamptic pregnancies, and in 194 girls and 166 boys of normotensive pregnancies, with similar anthropometric measures among mothers, performed at the beginning of the index pregnancy, and at follow-up, when their offspring were in early puberty.

Results: Among girls, the preeclampsia group had higher body mass (BMI 18.3 kg/m2 vs 17.5 kg/m2, p = 0.01) and larger waist circumference (63.7 cm vs 61.6 cm, p = 0.05) compared to the normotensive group, but the differences were restricted to the offspring of mothers with a high body mass (BMI >30 kg/m2). Among boys, we observed no differences in anthropometric measurements between groups.

Conclusions: The higher BMI and larger waist of daughters of women with preeclampsia was only present if their mothers were obese. These results suggest that preeclampsia in obese women may lead to a distinct disadvantage in body size for their daughters in early puberty.

Footnotes

  • Funding The research was funded by the NCI and is part of the global academic programme at the UT MD Anderson Cancer Center.

  • Competing interests None.

  • Provenance and Peer review Not commissioned; externally peer reviewed.

  • Ethics approval The study was approved by the Norwegian Data Inspectorate and by the Regional Committee for Ethics in Medical Research as well as the Institutional Review Board of the National Cancer Institute of the United States.

  • Patient consent Parental consent obtained.

This Article

  1. Abstract
  2. Full text
  3. PDF
  4. All versions of this article:
    1. adc.2008.150870v1
    2. 94/11/855 most recent

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

ADC is co-owned by the RCPCH and is the official journal of the European Academy of Paediatrics

Show me all >>