Objective To determine the influence of retinopathy of prematurity (ROP) on development in extremely preterm infants.
Method Using the NSW and ACT NICUS data collection, we have determined the influence of severity of ROP on development at 3 years of age in infants <29 weeks gestational age (GA) born between 1998–2001. Infants with PVL, grade 3 or 4 IVH, hydrocephalus, major congenital abnormalities, Stage 4 or 5 ROP, CP or severe hearing impairment were excluded. Infants with Stage 3 ROP were matched with no ROP, Stage 1 or Stage 2 ROP and compared using the Griffiths Mental Scale.
Results Sixty eight of 1214 surviving infants with Stage 3 ROP were included. Perinatal characteristics between groups were comparable. GA was significantly higher for infants with Stage 1 ROP and these infants had significantly higher scores with Hearing & Speech. See table.
Conclusion Severity of ROP was not related to development at 3 years of age in a population-based cohort of infants born <29 weeks GA.