Article Text

CORRELATION BETWEEN N-3 AND N-6 POLYUNSATURATED FATTY ACIDS IN MATERNAL AND CORD BLOOD SERUM LIPIDS AT DELIVERY
  1. T Marosvolgyi1,
  2. E Szabo1,
  3. R Noe1,
  4. G Boehm2,3,
  5. C Beermann2,
  6. M Weyermann4,
  7. H Brenner1,
  8. D Rothenbacher1,
  9. T Decsi1
  1. 1Department of Paediatrics, University of Pecs, Pecs, Hungary
  2. 2Danone Research, Center for Specialised Nutrition, Friedrichsdorf, Germany
  3. 3Sophia Childrenâs Hospital, Erasmus University, Rotterdam, The Netherlands
  4. 4Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany

Abstract

Aim To investigate the relationship between maternal and foetal fatty acid status at delivery.

Methods We investigated fatty acid composition of plasma phospholipids (PL) in mothers (n=76) and their healthy newborns by high resolution capillary gas chromatography.

Results We found significant positive correlations between linoleic acid (LA) and alpha-linolenic acid (ALA) in maternal plasma and LA in cord blood plasma and as well as between arachidonic acid (AA) and docosahexaenoic acid (DHA) in maternal plasma and AA in cord blood plasma. In contrast, we failed to find correlation between LA values in maternal and AA values in foetal plasma, or between ALA values in maternal and DHA values in foetal plasma. ALA in cord blood was significantly related to ALA and DHA in the mother. DHA in newborns was significantly positively related to AA and DHA in mothers (Table).

Conclusion Not maternal essential fatty acids (LA, ALA), but maternal long-chain polyunsaturated fatty acids (AA, DHA) are related significantly to AA and DHA status of the infant.

Marosvolgyi et al Spearman rho coefficients between maternal and infantile fatty acids

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