Article Text

HERPES SIMPLEX VIRUS INFECTION: POLYMORPHOUS MANIFESTATIONS
  1. M Suciu1,
  2. A M Rosenberg1,
  3. V Utescu1,
  4. O Cristiu1,
  5. C Cazan1
  1. 1Pediatric Clinic of Sibiu, Sibiu, Romania

Abstract

The spread of herpes infection is universal and omnipresent. The clinical findings are from the most commonly found in clinics to extremely polymorphous manifestations, difficult to diagnose. We report the case of a 15-year-old male patient without any medical history who was diagnosed in our clinic with laterocervical zoster herpes, Ramsey–Hunt syndrome. The diagnosis was established on clinical examination—zoster eruption, ear pain, auditory external channel pain, neck pain, minimal ipsilateral facial paralysis, losing of the taste sense, dizziness and constant ringing sound and laboratory investigations. We also report the case of an 11-year-old male patient without any important medical history who was diagnosed in our clinic with multiform erythema of infectious cause, probably implicating the herpes simplex virus, on an atopic condition with high values of E immunoglobulins and a history of drug allergy. The diagnosis was established on clinical examination—skin eruption with the aspect of “clout” and clear liquid vesicles on both ears and on the laboratory investigations and good response to local and oral therapy using antiviral and immunostimulating drugs.

The particularity of these cases comes from the difficulty of establishing a certain positive diagnosis of herpes virus infection, when lacking specific laboratory investigations, the diagnosis being based upon clinical examination (typical skin eruption) and laboratory tests. The good response to acyclovir treatment represents an additional argument in sustaining the diagnosis.

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