Article Text

COULD HYPERGLYCAEMIA AND TROPONIN I PREDICT OUTCOME IN INTENSIVE CARE AFTER CONGENITAL HEART SURGERY IN CHILDREN?
  1. S Di Bernardo1,
  2. M H Perez2,
  3. P Stucki2,
  4. J Cotting2
  1. 1Paediatrics Cardiology Unit, Department of Paediatrics, University Hospital CHUV, Lausanne, Switzerland
  2. 2PICU, Department of Paediatrics, University Hospital CHUV, Lausanne, Switzerland

Abstract

The objective of the study was to evaluate significance of hyperglycaemia and cardiac Troponin I (cTnI) after congenital heart surgery in children.

Retrospective cohort study with 279 children. Integrated values (area under the curve (AUC)) were calculated for the first 48 h for cTnI (48h-cTnI). Sustained hyperglycaemia was evaluated with the AUC normalised per hour (48h-Gluc/h). Maximal cTnI, first glucose value (Gluc1), 48h-cTnI and 48h-Gluc/h were correlated with duration of mechanical ventilation, ICU stay and mortality using cut-off values. See tables 1 and 2.

Conclusion

Di Bernardo et al Table 1

Di Bernardo et al Table 2

Hyperglycaemia is frequent after cardiac surgery and sustained in the first 48 hours. Admission glycaemia, cTnI max and 48h-cTnI are associated with a higher risk of mortality, prolonged duration of mechanical ventilation and prolonged length of stay in ICU.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.