Objective To evaluate changes in haemodynamics, tissue perfusion and ventilation due to a delayed sternal closure (DSC).
Patients and Methods Prospective study on 12 newborns weighing 1.9 to 4.2 (median 3.3) kg after biventricular corrective surgery. Haemodynamic parameters, serum lactate, and ventilation parameters studied by standard monitoring and femoral artery thermodilution technique (PiCCO). Values before, immediately after, and in regular intervals up to 48 hours after DSC were compared.
Results DSC caused significant decrease of systolic arterial pressure, cardiac output, cardiac function index, and stroke volume variation. Decrease in serum lactate was observed later in the course (table).
Conclusion DSC causes a temporary decrease of systolic blood pressure and cardiac output.
Support: IGA Grant NR-9046-3.
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