Objectives The analysis of developing infectious pathology causes and their monitoring in children aged 0–6 is vital and was therefore the aim of our investigation.

Methods Study of 1000 records of acute morbidity data from medical histories from children aged 0–6 over four generations (born in the 1970s, 1980s, 1990s and 2000s) was carried out.

Results Among boys and girls, enteritis, measles, chicken pox and epidemic parotitis in the general structure of morbidity were more than 80%. The morbidity rate in the category of infectious and parasitic diseases was higher in children of the 70s (boys) and the children of the 00s (girls) born and having lived in the maximal technogenic loadings conditions than at the children of 80s–90s (p<0.001). Parameters of diseases for chicken pox and measles in children were the highest. Girls from the 2000s were 15 times more likely to get measles than girls from the 70s. For boys high parameters of measles and chicken pox were seen in 2 generations (70s and 2000s).

Conclusion High parameters for infectious and parasitic diseases in 4 generations, despite vaccination, were marked. The highest rated disease was in girls from the 2000s (measles) and boys from the 70s (chicken pox). In boys an increase in diseases was observed through 2 generations, at girls through 1 generation. Further studying of this problem is necessary.