Article Text

RETROSPECTIVE INVESTIGATIONS OF CONGENITAL DEFECTS DEVELOPMENT IN NEWBORNS (5 GENERATIONS) IN THE LARGE SIBERIAN CITY
  1. N V Dedyulina1,
  2. S A Malchasyan2
  1. 1Chair of Hygiena, Omsk State Medical Academy, Omsk, Russia
  2. 2Bakulev Centre of Science of Surgery of Heart and Circulatory System, Scientific-Organizational Department, Moscow, Russia

Abstract

Objectives The determination of causes and risk factors for congenital defect development (CDD) continues to be vital to improve the system of monitoring losses of child health, and this has been the aim of our research.

Methods 2000 findings of CDD morbidity registed for first-year infants and obtained from their patient records for the period of 1960–2003 were used.

Results An increase of CDD morbidity was observed in children born in the 1960s compared with the generation of children born in the 1950s. CDD was 6 times higher in children in the 2000s than those who born in the 1970s (especially in boys). CDDs of the circulatory system were the main nosologic form of disease; in the 2000s data boys were 6 times more likely to have this condition than in the 1970s. CDD of the circulatory system were not significant in the 1970s for girls but in the generations from the 1990s and 2000s the frequency of such registrations has increased by 26 times. The children born in the 1990s appeared to be most susceptible to influence from ecological factors. Statistically significant connections of average force (0.64) with complex parameters of atmospheric air pollution and (0.68) with complex parameter of polluting water were found.

Conclusion CDD in children has increased by 6 times (especially in the male cohort). CDDs of the circulatory system were the main nosologic form of this class of diseases.

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