Objectives To investigate the incidence of infections with Klebsiella spp in the Pediatric ward of the Emergency Clinical Hospital in Constanta and to detect the sensitivity to antibiotics of isolated strains, during a period of one year.
Methods The pathological specimens were represented by urine, sputum, throat specimen, ear secretion, pus, stools. The disk diffusion method Kirby Bauer was used in the bacteriology laboratory for the detection of the sensitivity of the isolated strains and tested the sensitivity for 16 antibacterial drugs.
Results A total number of 38 strains have been isolated: 17 strains (44.76%) from urine, 6 strains (15.78%) in sputum, 2 strains (5.26%) in blood culture, 1 strain (2.63%) in ear secretion, and 12 strains (31.5%) in stool cultures. The sensitivity to antimicrobial agents of isolated strains was as follows: 29 (76.31%) sensitive to ciprofloxacin (the highest sensitivity in our study), 23 (60.52%) sensitive to amikacin, 25 (65.78%) to ceftazidime, 26 (68.42%) to imipenem, 20 (52.63%) to aztreonam, 21 (55.26%) to gentamycin, and 22 (57.84%) to netilmicin.
Conclusion Klebsiella spp are responsible for a significant number of hospital-acquired urinary infections, pneumonia, septicemias, wound infections, diarrhoea. The reservoir is the gastrointestinal tract and the hands of hospital personnel. They tend to aquire rapid resistance to antimicrobial drugs. In our study the best sensitivity was obtained for quinolones, imipenem and third generation of cephalosporins.