Article Text

DRAMATIC EFFECT OF NANDROLONE DECANOATE ON MOTOR DEVELOPMENT IN CEREBRAL PALSY
  1. A J Al Mosawi1
  1. 1Department of Pediatrics, Univesrsity Hospital in Al Kadhimiyia, Baghdad, Iraq

Abstract

Objectives There is no specific intervention to improve motor development in cerebral palsy (CP). The aim of this paper is to report the effect of nandrolone decanoate (ND) on motor development in a child with CP.

Method A 14-month-old boy with CP caused by birth asphyxia presented with delayed motor development associated with mild spasticity and hyperreflexia. On presentation he was unable to turn from the supine to the sitting position alone and was not able to maintain a sitting position when he was put in a sitting position. He was not crawling but he was occasionally rolling to the sides. He was able to catch a biscuit and eat it. His language was delayed and he was not capable of saying any word with meaning. The patient received 2 intra-muscular injections of ND 12.5 mg in an interval of 2 weeks. Estimation of the bone age was made using radiographs of the left wrist before the injection and 2 weeks after each injection.

Results The use of ND was associated with a dramatic effect on the motor development without the occurrence of any adverse effects. After one week the child was able to sit alone and was trying to stand. One week after the second injection the child was walking (holding furniture) confidently, and walking 1–2 steps alone.

Conclusion The novel use of ND in this child with CP resulted in a dramatic effect on motor development without the occurrence of unwanted effects or advancement of bone age.

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