Article Text

SEROLOGICAL TESTS ESPECIALLY SPECIFIC IMMUNOGLOBULIN E IN DIAGNOSIS AND TREATMENT OF PAEDIATRIC ASTHMA
  1. S Stankovic1,
  2. A Sulajmani1,
  3. M Mihajlovska1,
  4. R Stojkovska1
  1. 1Paediatric Department, General Hospital, Kumanovo, Macedonia

Abstract

The determination of allergen specific IgE is very important in childhood. They are useful on occasions when skin test could not be performed if asthma attack or eczema is active and treatment is being given. Specific IgE can be performed at any age. There are studies demonstrating association between serological tests and asthma in childhood.

Data were collected from 52 children 32 boys, 20 girls age 114 years. They had frequently experienced bronchoobstructions, family history and atopic dermatitis or recurrent wheezing early in life. First serological tests were positive for 39 of them, with mean values total IgE 371.45IUml, ECP 59.6ngml Immulite. Then spec.IgE tests RIDA Allergy screen were performed. Mean values were spec.IgE on Dermatophagoides pteronyssinus 47.05IUml in 31 cases 73, Derm. farinae 41.97IUml in 27 69, pollens 20.78IUml in 13 33, pets 16.35IUml in 8 20, fish 19.11IUml in 4 10.25, Penicillium notatum 15.09IUml in 3 7.6, egg white 21.03IUml in 10 25.6, cows milk 15.01IUml in 7 17.9, wheat flour 3.9IUml in 2 5.l, soya 2.9IUml in 3 7.6, peanuts 3.5IUml in 5 12.8.

Conclusion Serological tests are very useful for the diagnosis and management of paediatric asthma identification and avoidance of allergens and gradual continuous prophylactic treatment in stepwise approach. The only disadvantage of the method is its higher price but there is no risk for systemic reaction.

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