Article Text

SPECIFIC IMMUNOGLOBULIN E IN PEDIATRIC ALLERGIC RESPIRATORY DISEASE
  1. A Butnariu1,
  2. E Barbul2,
  3. C Boboc2,
  4. M Andreica1,
  5. M Marc1
  1. 1University of Medicine and Pharmacy Iuliu HaIeganu, ClujNapoca, Romania
  2. 2Clinical Hospital of Children, ClujNapoca, Romania

Abstract

For a quarter of a century the prevalence of allergic diseases has increased among children. There is a growing interest in the use of quantitative analysis of IgE antibody responses for allergy diagnostic purposes among children.

Objectives a to assess the specific IgE in children with allergic respiratory disease b to correlate the intensity of allergic reactions with the type of clinical manifestation of the allergic respiratory disease.

Methods a study group 200 children with allergic respiratory disease, with age between 2months17 years b Pediatric Panell immunoblot test, which contains 20 allergens and positive control.

Results Children with asthma represented 84 from the studied pediatric patients, 8 with recurrent wheezing and 8 with allergic rhinitis. Specific IgE were positive in 76 of patients Pediatric Panell. Monosensitivity was obtained in 6 of children and polisensitivity in 94 of them. The most frequent allergens with positive results were cat and dog hair, and dust mite. The intensity of allergic reactions was expressed in 4 levels. The most intense reactions level I were to allergens like dust mite and grass pollen, and they directly correlated with asthma.

Conclusions 1. Specific IgE were positive at 76 of children with allergic respiratory disease.

2. The most intense reactions were to allergens like dust mite and grass pollen, and they directly correlated with asthma.

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