Objective PROM complicates 10% of pregnancies which in 25% occur under 37 weeks of gestation and are named PPROM. This study evaluates the septicemia in neonates born with preterm premature rupture of the membrane.
Methods 100 neonates born with rupture of the membrane at 26–37 weeks gestation were studied at Alzahra hospital from June 2006 to February 2007. Data were analyzed by SPSS v.14 software.
Results The mean gestational age at the time of membrane rupture was 33.23±0.56 (range: 26–37 w). The latent phase was from 1 to 720 hours (mean 46.15±17.81 h). Among 100 studied newborns, 3 positive blood cultures (3%), with Staphylcoccus epidermidis, Staphylococcus aureus, and E coli were observed. We couldn’t demonstrate any significant relations between positive blood culture of neonates and laboratory and clinical symptoms of both the mother and neonate and the latent period. However, the relationship between positive blood culture of neonates and gestational age, was significant (P<0.05).
Conclusions The reported incidence of neonatal sepsis caused by PROM in western countries is 2–4%, and in PPROM it is about 5%. In our study this rate was 3%.
Considering the low incidence of neonatal sepsis caused by PPROM in this study, and in order to reduce the complications of long stay in hospital, it is recommended to perform the first blood culture after birth and maintain close observation of neonates for 24 hours, and if there is no clinical infectious symptoms, all the neonates can be discharged and the parents can be advised to get the blood culture results after 4 days.