Article Text

RENAL AND UROLOGICAL MANIFESTATIONS OF THALASSEMIA
  1. U H Al-Safy1,
  2. M Hesham2,
  3. M Attfy3,
  4. H Ameen,
  5. M Attfy,
  6. N AbdelSamd
  1. 1Hematology and Onology Unit, Pediatric Department, Zagazig University, Zagazig, Egypt
  2. 2Clinical Pathology Department, Zagazig University, Zagazig, Egypt
  3. 3Radiology Department, Zagazig University, Zagazig, Egypt

Abstract

Renal and urological manifestations in thalassemia patients can be attributed to chronic anemia, and iron overload as well as the side effects of iron chelation therapy. The purpose of this study is to describe the abnormalities of the kidney and urological system in patients with beta thalassemia. We analyzed the examination history as well as urine and blood of 50 well-maintained homozygous beta thalassemia patients. Blood and timed urine samples were obtained for hematological and biochemical tests for blood urea nitrogen (BUN), serum creatinine, creatinine clearance, serum sodium, urine osmolality, potassium, uric acid, ferritin, beta2 microglobulin and other radiological investigations. Our results revealed that the tubular function disorder, renal calculi, recurrent urinary tract infection and nocturnal enuresis were the renal and urologic problems in thalassemic patients.

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