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Varicella vaccination for HIV-infected children
  1. A Knorr1,
  2. E Hutchison2,
  3. A Finn3
  1. 1
    Paediatric Department, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain
  2. 2
    Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
  3. 3
    Institute of Child Life & Health, Bristol, UK
  1. Professor Adam Finn, Institute of Child Life & Health, Level 6, UBHT Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK; Adam.Finn{at}bristol.ac.uk

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Human immunodeficiency virus (HIV)-infected children are more likely to develop severe varicella and to die when infected than otherwise healthy children.1 2 In the absence of universal immunisation varicella remains prevalent.3 Secondary prophylaxis in exposed high-risk patients is expensive, invasive, carries the risk of side-effects and may not be implemented reliably. Primary prophylaxis with live-attenuated varicella vaccine has been shown to be safe and immunogenic and effective against both primary varicella and zoster recurrences in HIV-infected children …

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