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The list of neurological complications possibly associated with influenza is long and includes Reye’s syndrome, encephalitis, acute disseminated encephalomyelitis, Guillain-Barré syndrome, transverse myelitis and acute necrotising encephalopathy. Many of the reported cases of influenza-associated neurological disease have been in Japan, especially of acute necrotising encephalopathy. Now an 11-year review of influenza-associated encephalitis/encephalopathy has been reported from Toronto (Reshma Amin and colleagues. Pediatric Infectious Disease Journal 2008;27:390–5).
A prospective encephalitis register …