Article Text
Miscellanea
Angiotensin II receptor blockers to slow aortic root dilation in Marfan’s syndrome
Statistics from Altmetric.com
Marfan’s syndrome is an autosomal dominant condition affecting about 1 in 5000 people and is caused by mutations in the gene (FBN1) that encodes fibrillin-1. The main cause of premature death in people with Marfan’s syndrome is progressive dilation of the aortic root leading to dissection. Current medical treatment is mainly with β blockers. Experiments …