Article Text

PDF
Steroids in septic shock: the confusion continues
  1. Shane M Tibby
  1. Guy’s and St Thomas’ NHS Foundation Trust, London, UK; shane.tibby@gstt.nhs.uk

Statistics from Altmetric.com

Aneja and Carcillo’s review of adrenal insufficiency and the rationale for steroid use in sepsis is both concise and timely.1 Although they acknowledge that further studies are needed in paediatrics before recommending a 7 day course of hydrocortisone in catecholamine resistant septic shock, they suggest that the logic for this therapy is “compelling”, recommending a bolus of hydrocortisone followed by an infusion of up to 50 mg/kg/day in states of sepsis-induced relative adrenal insufficiency.

This compelling logic is incorporated within their statement that, among children with septic shock, survivors exhibit dramatically increased plasma levels of cortisol compared to non-survivors (Aneja and Carcillo, …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.