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Severity of obstructive apnoea in children with Down syndrome who snore
  1. Dominic A Fitzgerald,
  2. Annette Paul,
  3. Clare Richmond
  1. University of Sydney, The Children’s Hospital at Westmead, Sydney, Australia
  1. Correspondence to:
    Associate Professor Dominic A Fitzgerald
    Department of Respiratory Medicine, The Children’s Hospital at Westmead, Sydney, Locked Bag 4001, Westmead, NSW 2145, Australia; dominif2{at}chw.edu.au

Abstract

Diagnostic overnight polysomnograms of 33 children with Down syndrome who snored were reviewed. Mean age was 4.9 years, none had had adenotonsillectomy, 91% were non-obese (Down syndrome specific body mass index standard deviation score (BMI SDS) <+2.0) and yet 97% demonstrated obstructive sleep apnoea, with an average apnoea hypopnoea index (AHI) of 12.9 episodes per hour (normal <1) and an average oxygen desaturation of 4%. A higher AHI was associated with lower minimum Spo2, higher Tcco2 and higher number of arousals from sleep per hour (p<0.001). Polysomnography should be a routine investigation for children with Down syndrome who snore regardless of body habitus.

  • AHI, apnoea hypopnoea index
  • BMI SDS, body mass index standard deviation score
  • OSA, obstructive sleep apnoea
  • Spo2, oxygen saturation
  • Tcco2, transcutaneous carbon dioxide
  • snoring
  • obstructive sleep apnoea
  • polysomnography
  • Down syndrome

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Footnotes

  • Competing interests: None.

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