Article Text

PDF
Adverse effects of rapid isotonic saline infusion
  1. M Eisenhut
  1. Consultant Paediatrician, Luton & Dunstable Hospital, Lewsey Road, Luton LU4 0DZ, UK; michael_eisenhut@yahoo.com

Statistics from Altmetric.com

Neville et al reported on a randomised controlled trial of hypotonic versus isotonic saline for rehydration of children with gastroenteritis. They found that isotonic saline was superior with regards to correction of hyponatraemia.1 The majority of patients in the study received a “rapid replacement protocol” which entailed the infusion of 40 ml/kg of isotonic saline over 4 hours in the isotonic saline arm of the study. The authors did not report on important known adverse effects associated with rapid infusion of isotonic …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.