rss
Arch Dis Child 2006;91:608-609 doi:10.1136/adc.2004.071266
  • Short report

No clinical evidence of hidden vCJD in UK children

  1. C M Verity1,
  2. A M Winstone1,
  3. L Stellitano1,
  4. A Nicoll2,
  5. R G Will3
  1. 1Addenbrooke’s Hospital, Cambridge, UK
  2. 2Communicable Disease Surveillance Centre, London, UK
  3. 3National Creutzfeldt-Jakob Surveillance Unit, Western General Hospital, Edinburgh, UK
  1. Correspondence to:
    Dr Christopher M Verity
    Child Development Centre, Box 107, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 2QQ, UK; christopher.verity{at}addenbrookes.nhs.uk
  • Accepted 17 May 2005
  • Published Online First 31 October 2005

Abstract

Between May 1997 and November 2004 this national prospective surveillance study identified 1007 children with “progressive intellectual and neurological deterioration” (PIND). In most cases specific diagnoses were made, but of 92 undiagnosed children with PIND 46 had died and only four underwent full necropsy. There was no clinical evidence of variant Creutzfeldt-Jakob disease (vCJD) in these undiagnosed cases, but without necropsy it is not possible to exclude vCJD completely.

Footnotes

  • Published Online First 31 October 2005

This Article

  1. Abstract
  2. Full text
  3. PDF
  4. All versions of this article:
    1. adc.2004.071266v1
    2. 91/7/608 most recent

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

ADC is co-owned by the RCPCH and is the official journal of the European Academy of Paediatrics

Show me all >>