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Placental malaria and immunity to infant measles
  1. S Owens1,2,
  2. G Harper2,
  3. J Amuasi4,
  4. G Offei-Larbi4,
  5. J Ordi3,
  6. B J Brabin2,5
  1. 1MRC Laboratories, Atlantic Road, Fajara, The Gambia
  2. 2Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Liverpool, UK
  3. 3Department d’Anatomia Patologica, Universitat de Barcelona, Barcelona, Spain
  4. 4Komfo Anokye Teaching Hospital, Kumasi, Ghana
  5. 5Emma Kinderziekenhuis, Academic Medical Centre, University of Amsterdam, Netherlands
  1. Correspondence to:
    Professor Bernard Brabin
    Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5AQ, UK; b.j.brabin{at}liv.ac.uk

Abstract

The efficiency of transplacental transfer of measles specific antibody was assessed in relation to placental malaria. Infection at delivery was associated with a 30% decrease in expected cord measles antibody titres. Uninfected women who received anti-malarial drugs during pregnancy transmitted 30% more antibody than those who received no antimalarial drugs.

  • malaria
  • placenta
  • measles

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Footnotes

  • Competing interests: none declared

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