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Randomised controlled trial of combined paracetamol and ibuprofen for fever
  1. M D S Erlewyn-Lajeunesse1,
  2. K Coppens2,
  3. L P Hunt1,
  4. P J Chinnick2,
  5. P Davies2,
  6. I M Higginson2,
  7. J R Benger3
  1. 1Clinical Sciences at South Bristol, Faculty of Medicine, University of Bristol, UK
  2. 2Children’s Emergency Department, Bristol Royal Hospital for Children, Bristol, UK
  3. 3Faculty of Health and Social Care, University of the West of England, Bristol, UK
  1. Correspondence to:
    Dr M Erlewyn-Lajeunesse
    Institute of Child Life & Health, UBHT Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK; Mich.Lajeunesse{at}bristol.ac.uk

Abstract

A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.

  • acetaminophen
  • preschool
  • fever
  • ibuprofen

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Footnotes

  • Published Online First 7 February 2006

  • Funding: this study was funded by the Anthony Hopkins Memorial Prize, awarded by the Faculty of Accident and Emergency Medicine as an unrestricted award to the Emergency Department

  • Competing interests: none declared

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