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Antiepileptic drugs: combination therapy and interactions
  1. M Wagstaff

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Edited by Jerzy Majkowski, Blaise Bourgeois, Philip Patsalos and Richard Mattson. Cambridge: Cambridge University Press, 2005, £85.00 (approx. €125, $150), pp 496. ISBN 052182219x


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Combinations of antiepileptic drugs frequently cause concern to prescribers. Interactions are known to occur, and in paediatrics the use of polytherapy indicates a failure of monotherapy to control seizures. Polytherapy may occur when a second drug is introduced before the first is withdrawn, or as a long term measure in order to achieve seizure control.

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