Arch Dis Child 91:259-264 doi:10.1136/adc.2004.068684
  • Review

Current issues in the management of intestinal failure

  1. G L Gupte1,
  2. S V Beath1,
  3. D A Kelly1,
  4. A J W Millar1,
  5. I W Booth2
  1. 1Liver Unit, Birmingham Children’s Hospital, Birmingham, UK
  2. 2University of Birmingham, Institute of Child Health, Birmingham, UK
  1. Correspondence to:
    Dr G Gupte
    Consultant Paediatric Hepatologist, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham B4 6NH, UK; girish.gupte{at}
  • Accepted 15 November 2005


Successful long term parenteral nutrition has transformed the prognosis for children with irreversible intestinal failure in the last three decades, but has also highlighted the long term complications: intestinal failure associated liver disease; recurrent catheter sepsis; and impaired venous access. Recent advances in small bowel transplantation and non-transplant surgical techniques now offer hope of sustained survival in the future without parenteral nutrition.


  • Competing interests: none declared