Article Text

PDF
Perceptions of parents on the participation of their infants in clinical research
  1. A Gammelgaard1,
  2. L E Knudsen2,
  3. H Bisgaard3
  1. 1Department of Medical Philosophy and Clinical Theory, Institute of Public Health, University of Copenhagen, Copenhagen N, Denmark
  2. 2Department of Environmental Medicine, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark
  3. 3Danish Paediatric Asthma Centre, Department of Paediatrics, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark
  1. Correspondence to:
    A Gammelgaard
    Department of Medical Philosophy and Clinical Theory, Institute of Public Health, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark;a.gammelgaard{at}medphil.ku.dk

Abstract

Objective: To analyse the motivations and perceptions of parents on the participation of their infants and young children in a comprehensive and invasive clinical research study.

Methods: Semistructured qualitative interviews were conducted with 23 mothers with asthma whose infants and young children were participating in the Copenhagen Prospective Study on Asthma in Childhood. The interviews were audiotaped, transcribed and analysed using the template analysis method.

Results: Parents were motivated by altruism and by the opportunity to get their child checked regularly by medical experts to prevent the possible development of asthma. Parents found it very important that their children enjoyed their visits to the research clinic, and that they could withdraw from the study if their child started responding negatively to those visits. No apparent difference was seen in the attitude between the parents of children with lung or skin symptoms and those of healthy children.

Conclusions: It is possible to design and accomplish invasive clinical research on infants and young children in a manner that parents find ethically sound.

  • COPSAC, Copenhagen Prospective Study on Asthma in Childhood
  • CRU, clinical research unit

Statistics from Altmetric.com

Footnotes

  • Published Online First 4 July 2006

  • Funding: This study was supported by the Danish Pediatric Asthma Centre, the Research Centre for Environmental Health (ISMF) contract no 0-302-02-3/7, the CHILDRENGENONETWORK (QLK4-CT-2002-02198), Aase & Ejnar Danielsens Fund and the Lippmann Fund. The funders had no involvement in this work.

  • Competing interests: None declared.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Précis
    BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health