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Non-invasive testing for severe fetal anaemia

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The fetus with severe rhesus haemolytic disease may be at risk of dying from severe anaemia and in need of intrauterine blood transfusion. Standard testing includes repeated amniocentesis with spectrophotometric measurement of amniotic fluid bilirubin levels using change in optical density at wavelength 450 nm (ΔOD450). The risks of …

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