Nephrotic syndrome relapse: need for a better evidence based definition
- Paediatric Department, Sandwell General Hospital, West Bromwich B71 4HJ, UK; hassibnarchi@hotmail.com
Despite the occurrence of relapses, steroid sensitive nephrotic syndrome (SSNS) has a good long term prognosis. As it often heralds a clinical relapse, significant proteinuria (+++ or more on albustix) for ≥3 consecutive days (simplified as P3D in this letter) defines a relapse, resulting in steroid therapy before the onset of oedema. Proteinuria may be triggered by viral infections1 and does not always develop into a relapse.2
We have observed 24 consecutive episodes of asymptomatic P3D, without …
