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Arch Dis Child 2003;88:330-331 doi:10.1136/adc.88.4.330
  • Acute paediatrics

Metrorrhagia and precocious puberty revealing primary hypothyroidism in a child with Down’s syndrome

  1. W Chemaitilly1,
  2. C Thalassinos1,
  3. S Emond2,
  4. E Thibaud1
  1. 1Paediatric Endocrinology Department, Hôpital Necker Enfants Malades, Paris, France
  2. 2Paediatric Radiology Department, Hôpital Necker Enfants Malades, Paris, France
  1. Correspondence to:
    Dr W Chemaitilly, Paediatric Endocrinology Department, Hôpital Necker Enfants Malades, Paris, France;
    wassimnet{at}aol.com
  • Accepted 18 September 2002

Abstract

We report a child with Down’s syndrome in whom metrorrhagia and precocious puberty revealed primary autoimmune hypothyroidism. The patient had a decreased growth velocity, exaggerated weight gain, bone age delay, and bilaterally enlarged multicystic ovaries. Delays in the diagnosis and treatment of hypothyroidism can lead to this peculiar presentation.

Footnotes

    Responses to this article

    • Hypothyroidism revealed following metrorrhagia in a child with Down's Syndrome
      • Richard A Banks
      ADC published online October 19, 2004

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