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Acute paediatrics
Aplastic anaemia associated with parvovirus B19 infection
  1. X H Qian1,
  2. G C Zhang1,
  3. X Y Jiao2,
  4. Y J Zheng1,
  5. Y H Cao1,
  6. D L Xu1,
  7. C S Chen3
  1. 1Department of Paediatrics, Xijing Hospital, the Fourth Military Medical University, Xi’an, PR China
  2. 2Institute of Neurosciences, Chinese PLA, Xi’an, PR China
  3. 3Department of Health Statistics, the Fourth Military Medical University, Xi’an, PR China
  1. Correspondence to:
    Dr X H Qian, Department of Paediatrics, Xijing Hospital, the Fourth Military Medical University, Xi’an, 710032, PR China; qianxinhong{at}21cn.com

Abstract

Parvovirus B19 involvement was investigated in 30 children with severe aplastic anaemia. Active or recent parvovirus B19 infection, as shown by B19 DNA viraemia, positive B19 specific IgM antibodies, or both, was diagnosed in six patients. There were no other plausible causes. We suggest that parvovirus B19 infection might be associated with severe aplastic anaemia.

  • human parvovirus B19
  • aplastic anaemia
  • EI, erythema infectiosum
  • PCR, polymerase chain reaction
  • SAA, severe aplastic anaemia

https://doi.org/10.1136/adc.87.5.436

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